Eosinophil Granulocyte - Treatment

Treatment

Treatments used to combat autoimmune diseases and conditions caused by eosinophils include:

  • corticosteroids- promote apoptosis. Numbers of eosinophils in blood are rapidly reduced
  • monoclonal antibody therapy- e.g., mepoluzimab or reslizumab against IL-5, prevents eosinophilopoiesis
  • antagonists of leukotriene synthesis or receptors
  • Gleevec (STI571)- inhibits PDGF-BB in hypereosinophilic leukemia

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