Organic Synthesis
Sulfonamides can be prepared in the laboratory in many ways. For example, by the reaction of sulfonyl chlorides with amines in the synthesis of sulfonylmethylamide. A readily available sulfonyl chloride source is tosyl chloride.
Triflimide or triflimidic acid HN(Tf)2 (bis(trifluoromethane)sulfonimide) is the formal adduct of triflic acid and ammonia. Phenyl triflimide is a triflating reagent. The related metal triflimidates are used as catalysts. The anion bistriflimide is hydrophobic.
Read more about this topic: Sulfonamide (chemistry)
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