Sulfonamide (chemistry)

Sulfonamide (chemistry)

In chemistry, the sulfonamide functional group (also spelt sulphonamide ) is -S(=O)2-NH2, a sulfonyl group connected to an amine group.

A sulfonamide (compound) is a compound that contains this group. The general formula is RSO2NH2, where R is some organic group. For example, "methanesulfonamide" is CH3SO2NH2. Any sulfonamide can be considered as derived from a sulfonic acid by replacing a hydroxyl group with an amine group.

In medicine, the term "sulfonamide" is sometimes used as a synonym for sulfa drug, a derivative or variation of sulfanilamide.

Read more about Sulfonamide (chemistry):  Organic Synthesis, Sulfinamides