A Southern blot is a method routinely used in molecular biology for detection of a specific DNA sequence in DNA samples. Southern blotting combines transfer of electrophoresis-separated DNA fragments to a filter membrane and subsequent fragment detection by probe hybridization. The method is named after its inventor, the British biologist Edwin Southern. Other blotting methods (i.e., western blot, northern blot, eastern blot, southwestern blot) that employ similar principles, but using RNA or protein, have later been named in reference to Edwin Southern's name. As the technique was eponymously named, Southern blot is capitalized as is conventional for proper nouns. The names for other blotting methods may follow this convention, by analogy.
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Famous quotes containing the words southern and/or blot:
“I think those Southern writers [William Faulkner, Carson McCullers] have analyzed very carefully the buildup in the South of a special consciousness brought about by the self- condemnation resulting from slavery, the humiliation following the War Between the States and the hope, sometimes expressed timidly, for redemption.”
—Jimmy Carter (James Earl Carter, Jr.)
“Lo, thus, as prostrate, ‘In the dust I write
My heart’s deep languor and my soul’s sad tears.’
Yet why evoke the spectres of black night
To blot the sunshine of exultant years?”
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