Serum Sickness - Symptoms

Symptoms

Symptoms can take as long as 14 days after exposure to appear, and may include signs and symptoms commonly associated with allergic reactions or infections.

  • rashes
  • itching
  • joint pain (arthralgia), especially finger and toe joints
  • fever, as high as 104°F and usually appears before rash
  • lymphadenopathy (swelling of lymph nodes), particularly near the site of injection, head and neck
  • malaise
  • hypotension (decreased blood pressure)
  • splenomegaly (enlarged spleen)
  • glomerulonephritis
  • proteinuria
  • hematuria
  • shock

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