Degradation
Different mRNAs within the same cell have distinct lifetimes (stabilities). In bacterial cells, individual mRNAs can survive from seconds to more than an hour; in mammalian cells, mRNA lifetimes range from several minutes to days. The greater the stability of an mRNA the more protein may be produced from that mRNA. The limited lifetime of mRNA enables a cell to alter protein synthesis rapidly in response to its changing needs. There are many mechanisms that lead to the destruction of a mRNA, some of which are described below.
Read more about this topic: Messenger RNA
Famous quotes containing the word degradation:
“Self-alienation is the source of all degradation as well as, on the contrary, the basis of all true elevation. The first step will be a look inward, an isolating contemplation of our self. Whoever remains standing here proceeds only halfway. The second step must be an active look outward, an autonomous, determined observation of the outer world.”
—Novalis [Friedrich Von Hardenberg] (1772–1801)
“History is nothing but a procession of false Absolutes, a series of temples raised to pretexts, a degradation of the mind before the Improbable.”
—E.M. Cioran (b. 1911)
“Gradually we come to admit that Shakespeare understands a greater extent and variety of human life than Dante; but that Dante understands deeper degrees of degradation and higher degrees of exaltation.”
—T.S. (Thomas Stearns)