Messenger RNA - Degradation

Degradation

Different mRNAs within the same cell have distinct lifetimes (stabilities). In bacterial cells, individual mRNAs can survive from seconds to more than an hour; in mammalian cells, mRNA lifetimes range from several minutes to days. The greater the stability of an mRNA the more protein may be produced from that mRNA. The limited lifetime of mRNA enables a cell to alter protein synthesis rapidly in response to its changing needs. There are many mechanisms that lead to the destruction of a mRNA, some of which are described below.

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Famous quotes containing the word degradation:

    The three great problems of this century, the degradation of man in the proletariat, the subjection of women through hunger, the atrophy of the child by darkness.
    Victor Hugo (1802–1885)

    In her present ignorance, woman’s religion, instead of making her noble and free, by the wrong application of great principles of right and justice, has made her bondage but more certain and lasting, her degradation more hopeless and complete.
    Elizabeth Cady Stanton (1815–1902)

    Why, since man and woman were created for each other, had He made their desires so dissimilar? Why should one class of women be able to dwell in luxurious seclusion from the trials of life, while another class performed their loathsome tasks? Surely His wisdom had not decreed that one set of women should live in degradation and in the end should perish that others might live in security, preserve their frappeed chastity, and in the end be saved.
    Madeleine [Blair], U.S. prostitute and “madam.” Madeleine, ch. 10 (1919)