Insulin-like Growth Factor
The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate with their physiologic environment. This complex system (often referred to as the IGF "axis") consists of two cell-surface receptors (IGF1R and IGF2R), two ligands (IGF-1 and IGF-2), a family of six high-affinity IGF-binding proteins (IGFBP-1 to IGFBP-6), as well as associated IGFBP degrading enzymes, referred to collectively as proteases.
Read more about Insulin-like Growth Factor: IGF1/GH Axis, IGF Receptors, Organs and Tissues Affected By IGF-1, IGF-Binding Proteins, Diseases Affected By IGF
Famous quotes containing the words growth and/or factor:
“Parents find many different ways to work their way through the assertiveness of their two-year-olds, but seeing that assertiveness as positive energy being directed toward growth as a competent individual may open up some new possibilities.”
—Fred Rogers (20th century)
“You factor in racism as a reality and you keep moving.”
—Jewell Jackson McCabe (b. 1945)