Inductively coupled plasma mass spectrometry (ICP-MS) is a type of mass spectrometry which is capable of detecting metals and several non-metals at concentrations as low as one part in 1012 (part per trillion). This is achieved by ionizing the sample with inductively coupled plasma and then using a mass spectrometer to separate and quantify those ions.
Compared to atomic absorption techniques, ICP-MS has greater speed, precision, and sensitivity. However, analysis by ICP-MS is also more susceptible to trace contaminants from glassware and reagents. In addition, the presence of some ions can interfere with the detection of other ions.
The variety of applications exceeds that of ICP-OES and includes isotopic speciation. Due to possible applications in nuclear technologies, ICP-MS hardware is a subject for special exporting regulations.
Read more about Inductively Coupled Plasma Mass Spectrometry: Routine Maintenance, Metal Speciation, Quantification of Proteins and Biomolecules, Sample Preparation, Elemental Analysis, Usage
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