Growth Factor - Classes of Growth Factors

Classes of Growth Factors

Individual growth factor proteins tend to occur as members of larger families of structurally and evolutionarily related proteins. There are many families, which are listed below:

This list is incomplete; you can help by expanding it.
  • Adrenomedullin (AM)
  • Angiopoietin (Ang)
  • Autocrine motility factor
  • Bone morphogenetic proteins (BMPs)
  • Brain-derived neurotrophic factor (BDNF)
  • Epidermal growth factor (EGF)
  • Erythropoietin (EPO)
  • Fibroblast growth factor (FGF)
  • Glial cell line-derived neurotrophic factor (GDNF)
  • Granulocyte colony-stimulating factor (G-CSF)
  • Granulocyte macrophage colony-stimulating factor (GM-CSF)
  • Growth differentiation factor-9 (GDF9)
  • Hepatocyte growth factor (HGF)
  • Hepatoma-derived growth factor (HDGF)
  • Insulin-like growth factor (IGF)
  • Migration-stimulating factor
  • Myostatin (GDF-8)
  • Nerve growth factor (NGF) and other neurotrophins
  • Platelet-derived growth factor (PDGF)
  • Thrombopoietin (TPO)
  • Transforming growth factor alpha(TGF-α)
  • Transforming growth factor beta(TGF-β)
  • Tumor_necrosis_factor-alpha(TNF-α)
  • Vascular endothelial growth factor (VEGF)
  • Wnt Signaling Pathway
  • placental growth factor (PlGF)
  • (FBS)
  • IL-1- Cofactor for IL-3 and IL-6. Activates T cells.
  • IL-2- T-cell growth factor. Stimulates IL-1 synthesis. Activates B-cells and NK cells.
  • IL-3- Stimulates production of all non-lymphoid cells.
  • IL-4- Growth factor for activated B cells, resting T cells, and mast cells.
  • IL-5- Induces differentiation of activated B cells and eosinophils.
  • IL-6- Stimulates Ig synthesis. Growth factor for plasma cells.
  • IL-7- Growth factor for pre-B cells.


Stimulates cell cycle from G0 phase to G1 phase

Read more about this topic:  Growth Factor

Famous quotes containing the words classes of, classes, growth and/or factors:

    “The want of education and moral training is the only real barrier that exists between the different classes of men. Nature, reason, and Christianity recognize no other. Pride may say Nay; but Pride was always a liar, and a great hater of the truth.”
    —Susanna Moodie (1803–1885)

    “The want of education and moral training is the only real barrier that exists between the different classes of men. Nature, reason, and Christianity recognize no other. Pride may say Nay; but Pride was always a liar, and a great hater of the truth.”
    —Susanna Moodie (1803–1885)

    “Every child has an inner timetable for growth—a pattern unique to him. . . . Growth is not steady, forward, upward progression. It is instead a switchback trail; three steps forward, two back, one around the bushes, and a few simply standing, before another forward leap.”
    —Dorothy Corkville Briggs (20th century)

    “Language makes it possible for a child to incorporate his parents’ verbal prohibitions, to make them part of himself....We don’t speak of a conscience yet in the child who is just acquiring language, but we can see very clearly how language plays an indispensable role in the formation of conscience. In fact, the moral achievement of man, the whole complex of factors that go into the organization of conscience is very largely based upon language.”
    —Selma H. Fraiberg (20th century)