Mathematics
Consider a single gene locus with the alleles, which have the fitnesses and the allele frequencies respectively. Ignoring frequency-dependent selection, then genetic load may be calculated as:
where is the maximum value of the fitnesses and is mean fitness which is calculated as the mean of all the fitnesses weighted by their corresponding allele frequency:
where the allele is and has the fitness and frequency and respectively.
When the, then (1) simplifies to
Read more about this topic: Genetic Load
Famous quotes containing the word mathematics:
“Why does man freeze to death trying to reach the North Pole? Why does man drive himself to suffer the steam and heat of the Amazon? Why does he stagger his mind with the mathematics of the sky? Once the question mark has arisen in the human brain the answer must be found, if it takes a hundred years. A thousand years.”
—Walter Reisch (1903–1963)
“... though mathematics may teach a man how to build a bridge, it is what the Scotch Universities call the humanities, that teach him to be civil and sweet-tempered.”
—Amelia E. Barr (1831–1919)
“In mathematics he was greater
Than Tycho Brahe, or Erra Pater:
For he, by geometric scale,
Could take the size of pots of ale;
Resolve, by sines and tangents straight,
If bread and butter wanted weight;
And wisely tell what hour o’ th’ day
The clock doth strike, by algebra.”
—Samuel Butler (1612–1680)