Deep Brain Stimulation - Potential Complications and Side Effects

Potential Complications and Side Effects

While DBS is helpful for some patients, there is also the potential for neuropsychiatric side effects. Reports in the literature describe the possibility of apathy, hallucinations, compulsive gambling, hypersexuality, cognitive dysfunction, and depression. However, these may be temporary and related to correct placement and calibration of the stimulator and so are potentially reversible. A 2006 study of 99 Parkinson's patients who had undergone DBS suggested a decline in executive functions relative to patients who had not undergone DBS, accompanied by problems with word generation, attention and learning. About 9% of patients had psychiatric events, which ranged in severity from a relapse in voyeurism to a suicide attempt. Most patients in this trial reported an improvement in their quality of life following DBS, and there was an improvement in their physical functioning.

Because the brain can shift slightly during surgery, there is the possibility that the electrodes can become displaced or dislodged. This may cause more profound complications such as personality changes, but electrode misplacement is relatively easy to identify using CT. There may also be complications of surgery, such as bleeding within the brain.

After surgery, swelling of the brain tissue, mild disorientation and sleepiness are normal. After 2–4 weeks, there is a follow-up to remove sutures, turn on the neurostimulator and program it.

Read more about this topic:  Deep Brain Stimulation

Famous quotes containing the words potential, side and/or effects:

    The real community of man ... is the community of those who seek the truth, of the potential knowers.
    Allan Bloom (1930–1992)

    Deliberation. The act of examining one’s bread to determine which side it is buttered on.
    Ambrose Bierce (1842–1914)

    The ultimate result of shielding men from the effects of folly, is to fill the world with fools.
    Herbert Spencer (1820–1903)