Competitive Inhibition - Equation

Equation

Competitive inhibition increases the apparent value of the Michaelis-Menten constant, such that initial rate of reaction, is given by

where, is the inhibitor's dissociation constant and is the inhibitor concentration.

remains the same because the presence of the inhibitor can be overcome by higher substrate concentrations., the substrate concentration that is needed to reach, increases with the presence of a competitive inhibitor. This is because the concentration of substrate needed to reach with an inhibitor is greater than the concentration of substrate needed to reach without an inhibitor.

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