In biology the active site is part of an enzyme where substrates bind and undergo a chemical reaction. The majority of enzymes are proteins but RNA enzymes called ribozymes also exist. The active site of an enzyme is usually found in a cleft or pocket that is lined by amino acid residues (or nucleotides in ribozymes) that participate in recognition of the substrate. Residues that directly participate in the catalytic reaction mechanism are called active site residues.
Read more about Active Site: Binding Mechanism, Chemistry
Famous quotes containing the words active and/or site:
“The sense of an entailed disadvantage—the deformed foot doubtfully hidden by the shoe, makes a restlessly active spiritual yeast, and easily turns a self-centred, unloving nature into an Ishmaelite. But in the rarer sort, who presently see their own frustrated claim as one among a myriad, the inexorable sorrow takes the form of fellowship and makes the imagination tender.”
—George Eliot [Mary Ann (or Marian)
“The site of the true bottomless financial pit is the toy store. It’s amazing how much a few pieces of plastic and paper will sell for if the purchasers are parents or grandparent, especially when the manufacturers claim their product improves a child’s intellectual or physical development.”
—Lawrence Kutner (20th century)