Acquired Resistance
Almost all anti-microbials, including anti-virals, are subject to drug resistance as the pathogens mutate over time, becoming less susceptible to the treatment. For instance, a recent study published in Nature Biotechnology emphasized the urgent need for augmentation of oseltamivir (Tamiflu) stockpiles with additional antiviral drugs including zanamivir (Relenza) based on an evaluation of the performance of these drugs in the scenario that the 2009 H1N1 'Swine Flu' neuraminidase (NA) were to acquire the tamiflu-resistance (His274Tyr) mutation which is currently widespread in seasonal H1N1 strains.
Read more about this topic: Antiviral Drug
Famous quotes containing the words acquired and/or resistance:
“You in the West have a problem. You are unsure when you are being lied to, when you are being tricked. We do not suffer from this; and unlike you, we have acquired the skill of reading between the lines.”
—Zdenek Urbának (b. 1917)
“High treason, when it is resistance to tyranny here below, has its origin in, and is first committed by, the power that makes and forever re-creates man.”
—Henry David Thoreau (1817–1862)