Acquired Resistance
Almost all anti-microbials, including anti-virals, are subject to drug resistance as the pathogens mutate over time, becoming less susceptible to the treatment. For instance, a recent study published in Nature Biotechnology emphasized the urgent need for augmentation of oseltamivir (Tamiflu) stockpiles with additional antiviral drugs including zanamivir (Relenza) based on an evaluation of the performance of these drugs in the scenario that the 2009 H1N1 'Swine Flu' neuraminidase (NA) were to acquire the tamiflu-resistance (His274Tyr) mutation which is currently widespread in seasonal H1N1 strains.
Read more about this topic: Antiviral Drug
Famous quotes containing the words acquired and/or resistance:
“Minerva House ... was “a finishing establishment for young ladies,” where some twenty girls of the ages from thirteen to nineteen inclusive, acquired a smattering of everything and a knowledge of nothing.”
—Charles Dickens (1812–1870)
“War is pillage versus resistance and if illusions of magnitude could be transmuted into ideals of magnanimity, peace might be realized.”
—Marianne Moore (1887–1972)