Alcohol Dehydrogenase
Alcohol dehydrogenases (ADH) (EC 1.1.1.1) are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH). In humans and many other animals, they serve to break down alcohols that otherwise are toxic, and they also participate in generation of useful aldehyde, ketone, or alcohol groups during biosynthesis of various metabolites. In yeast, plants, and many bacteria, some alcohol dehydrogenases catalyze the opposite reaction as part of fermentation to ensure a constant supply of NAD+.
Read more about Alcohol Dehydrogenase: Evolution, Discovery, Properties, Active Site, Structural Zinc Site, Applications
Famous quotes containing the word alcohol:
“The sacrifice to Legba was completed; the Master of the Crossroads had taken the loas’ mysterious routes back to his native Guinea.
Meanwhile, the feast continued. The peasants were forgetting their misery: dance and alcohol numbed them, carrying away their shipwrecked conscience in the unreal and shady regions where the savage madness of the African gods lay waiting.”
—Jacques Roumain (1907–1945)