Alcohol Dehydrogenase
Alcohol dehydrogenases (ADH) (EC 1.1.1.1) are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH). In humans and many other animals, they serve to break down alcohols that otherwise are toxic, and they also participate in generation of useful aldehyde, ketone, or alcohol groups during biosynthesis of various metabolites. In yeast, plants, and many bacteria, some alcohol dehydrogenases catalyze the opposite reaction as part of fermentation to ensure a constant supply of NAD+.
Read more about Alcohol Dehydrogenase: Evolution, Discovery, Properties, Active Site, Structural Zinc Site, Applications
Famous quotes containing the word alcohol:
“Some parents feel that if they introduce their children to alcohol gradually in the home environment, the children will learn to use alcohol in moderation. I’m not sure that’s such a good idea. First of all, alcohol is not healthy for the growing child. Second, introducing alcohol to a child suggests that you condone drinking—even to the point where you want to teach your child how to drink.”
—Lawrence Balter (20th century)