Zonule of Zinn - Anatomy

Anatomy

The zonule of Zinn is split into two layers: a thin layer, which lines the hyaloid fossa, and a thicker layer, which is a collection of zonular fibers. Together, the fibers are known as the suspensory ligament of the lens. The zonules are about 1–2 μ in diameter.

When colour granules are displaced from the Zonules of Zinn (by friction against the lens), the irises slowly fade. In some cases those colour granules clog the channels and lead to Glaucoma Pigmentosa.

The zonules are primary made of fibrillin, a connective tissue protein. Mutations in the fibrillin gene lead to the condition Marfans Syndrome, and consequences include an increased risk of lens dislocation.

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