Zabdiel Boylston, FRS (1679 in Brookline, Massachusetts – March 2, 1766) was a physician in the Boston area. He apprenticed with his father, an English surgeon named Thomas Boylston. He also studied under the Boston physician Dr. Cutler, never attending a formal medical school (the first medical school in North America was not founded until 1765).
Boylston is known for holding several "firsts" for an American-born physician: He performed the first surgical operation by an American physician, the first removal of gall bladder stones in 1710, and was the first to remove a breast tumor in 1718.
He was a great uncle of both president John Adams, and philanthropist Ward Nicholas Boylston.
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