Yosef Chaim is the name of:
- Chacham Yosef Chaim of Baghdad (1832–1909), better known as the Ben Ish Chai ("Son of Man (who) Lives")
- Yosef Chaim Brenner (1881–1921), a pioneer in Hebrew literature
- Rabbi Yosef Chaim Sonnenfeld (1848–1932), anti-Zionist Rav of Jerusalem