Yitzchak Isaac of Zidichov (1805–1873) was a noted Hasidic rabbi. He was the son of Rabbi Yisachar Barish, who was the brother of Rabbi Tzvi Hirsh of Zidichov (1763–1831). Rabbi Yitzchak Isaac was a close disciple of Rabbi Tzvi Hirsh of Zidichov until the latter's death. He later studied under Rabbi Shalom of Belz .
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“My mother made me a scientist without ever intending to. Every other Jewish mother in Brooklyn would ask her child after school: So? Did you learn anything today? But not my mother. “Izzy,” she would say, “did you ask a good question today?” That difference—asking good questions—made me become a scientist.”
—Isidor Isaac Rabi (20th century)