Yellowhead disease (YHD) is a viral infection of shrimp and prawn, in particular of the giant tiger prawn (Penaeus monodon), one of the two major species of farmed shrimp. The disease is highly lethal and contagious, killing shrimp quickly. Outbreaks of this disease have wiped out in a matter of days the entire populations of many shrimp farms that cultivated P. monodon, i.e. particularly Southeast Asian farms. In Thai, the disease is called Hua leung.
The disease is caused by the yellowhead virus (YHV), a positive-sense single-stranded RNA virus related to coronaviruses and arteriviruses. A closely related virus is the gill-associated virus (GAV), which is the type species of the genus Okavirus.
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“Is not disease the rule of existence? There is not a lily pad floating on the river but has been riddled by insects. Almost every shrub and tree has its gall, oftentimes esteemed its chief ornament and hardly to be distinguished from the fruit. If misery loves company, misery has company enough. Now, at midsummer, find me a perfect leaf or fruit.”
—Henry David Thoreau (18171862)