XX male syndrome (also called de la Chapelle syndrome, for a researcher who characterized it in 1972) is a rare sex chromosomal disorder. Usually it is caused by unequal crossing over between X and Y chromosomes during meiosis in the father, which results in the X chromosome containing the normally-male SRY gene. When this X combines with a normal X from the mother during fertilization, the result is an XX male.
This syndrome occurs in approximately four or five in 100,000 individuals, making it less common than Klinefelter syndrome.
Read more about XX Male Syndrome: Presentation, Clinical Diagnosis, Pathophysiology
Famous quotes containing the words male and/or syndrome:
“I say that male and female are cast in the same mold; except for education and habits, the difference is not great.”
—Michel de Montaigne (1533–1592)
“Women are taught that their main goal in life is to serve others—first men, and later, children. This prescription leads to enormous problems, for it is supposed to be carried out as if women did not have needs of their own, as if one could serve others without simultaneously attending to one’s own interests and desires. Carried to its “perfection,” it produces the martyr syndrome or the smothering wife and mother.”
—Jean Baker Miller (20th century)