XPC (gene)

XPC (gene)

Identifiers Symbols XPC; RAD4; XP3; XPCC External IDs OMIM: 613208 MGI: 103557 HomoloGene: 3401 GeneCards: XPC Gene

Gene Ontology
Molecular function	• loop DNA binding • bubble DNA binding • damaged DNA binding • single-stranded DNA binding • protein binding
Cellular component	• nucleus • nucleoplasm • cytoplasm • XPC complex
Biological process	• cell cycle checkpoint • nucleotide-excision repair, DNA damage recognition • nucleotide-excision repair, DNA damage removal • DNA repair • nucleotide-excision repair • response to UV-B • intra-S DNA damage checkpoint • response to drug
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7508 22591 Ensembl ENSG00000154767 ENSMUSG00000030094 UniProt Q01831 P51612 RefSeq (mRNA) NM_001145769 NM_009531 RefSeq (protein) NP_001139241 NP_033557 Location (UCSC) Chr 3:
14.19 – 14.22 Mb Chr 6:
91.49 – 91.52 Mb PubMed search

Xeroderma pigmentosum, complementation group C, also known as XPC, is a protein which in humans is encoded by the XPC gene. XPC is involved in the recognition of bulky DNA adducts in nucleotide excision repair.