XK (protein) - Clinical Significance

Clinical Significance

The Kx antigen plays a role in matching blood for blood transfusions.

Mutation of XK protein may lead to McLeod syndrome, a multi-system disorder characterized by hemolytic anemia, myopathy, acanthocytosis, and chorea.

XK is located on the X chromosome and absence of the XK protein is an X-linked disease.

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