Regular writers
- Chris Claremont, 1991
- Plots from Jim Lee and scripts by John Byrne or Scott Lobdell, 1991–1992
- Fabian Nicieza, 1992–1995
- Scott Lobdell, 1995–1997
- Joe Kelly, 1997–1999
- Alan Davis, 1999–2000
- Chris Claremont, 2000-2001
- Scott Lobdell, 2001
- Grant Morrison, 2001–2004
- Chuck Austen, 2004
- Peter Milligan, 2005–2006
- Mike Carey, 2006–2011
- Christos Gage, 2012
- Simon Spurrier, 2012–
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Regular artists
- Jim Lee, 1991–1992
- Andy Kubert, 1992–1996
- Carlos Pacheco, 1997–1998
- Adam Kubert, 1998–1999
- Alan Davis, 1999–2000
- Leinil Francis Yu, 2000–2001
- Frank Quitely, 2001–2003
- Other artists, including Igor Kordey and Ethan Van Sciver, often illustrated issues because Quitely was running very far behind on deadlines.
- No regular artist, 2003–2004
- Several illustrators, notably Phil Jimenez and Marc Silvestri, completed brief stints on the book due to deadline complications with previous art teams.
- Salvador Larroca, 2004–2006
- Humberto Ramos, 2006–2007
- Chris Bachalo, 2006–2008
- Scot Eaton, 2008–2009
- Other artists used for the flashback sequences throughout Xavier's quest include John Romita Jr., Greg Land, Billy Tan, and Mike Deodato.
- Daniel Acuña, 2009
- Clay Mann, 2010
- David Baldeon, 2012
- Tat Eng Huat, 2012–
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