William or Bill Owens may refer to:
- Bill Owens (baseball) (1901–1999), Negro league baseball player
- Bill Owens (congressman) (born 1949), Congressman of New York's 23rd congressional district
- Bill Owens (Colorado politician) (born 1950), former governor of Colorado
- Bill Owens (photographer) (born 1938), known for his photographs of American suburbia
- Billy Owens (born 1969), former American professional basketball player
- William A. Owens (1905–1990), American author
- William C. Owens, Jr. (born 1947), Democratic member of the North Carolina General Assembly
- William Claiborne Owens (1849–1925), U.S. Representative from Kentucky
- William Owens (admiral) (born 1940), former Vice Chairman, Joint Chiefs of Staff, also former CEO of Nortel
- William Owens (Canadian politician) (1840–1917)
- William Owens, former chief financial officer of HealthSouth Corporation