William Osborne or Osborn may refer to
- William Osborne (umpire), National League umpire in 1876
- William H. Osborne (born 1960), former president and CEO of Federal Signal Corporation
- William G. Osborne, respondent in District Attorney's Office v. Osborne, a U.S. Supreme Court case
- Will Osborne (1875–?), Wales international rugby player
- William Osborn (Medal of Honor) (1837–1887), American soldier and Medal of Honor recipient
- William A. Osborn (born 1947), American bank executive
- William Church Osborn (1862–1951), New York State Democratic Committee Chairman, 1914–1916
- William H. Osborn (1821–1894), American railroad tycoon
Famous quotes containing the word osborne:
“Miss Western: Tell me, child, what objections can you have to the young gentleman?
Sophie: A very solid objection, in my opinion. I hate him.
Miss Western: Well, I have known many couples who have entirely disliked each other, lead very comfortable, genteel lives.”
—John Osborne (1929–1994)