William Moseley is the name of:
- Bill Moseley (born 1951), American film actor and musician
- William Moseley (actor) (born 1987), English actor from The Chronicles of Narnia
- William A. Moseley (1798–1873), United States Representative from New York
- William Dunn Moseley, Governor of the U.S. state of Florida
- William G. Moseley, geographer at Macalester College
- William Mosley (born 1989), American basketball player