Early Life
Cullen was born in Hamilton, Lanarkshire. His father William was a lawyer retained by the Duke of Hamilton as factor, and his mother was Elizabeth Roberton of Whistlebury. He studied at the Old Grammar School of Hamilton (renamed in 1848 The Hamilton Academy), then, in 1726, began a General Studies arts course at the University of Glasgow. He began his medical training as apprentice to John Paisley, a Glasgow apothecary surgeon, then spent 1729 as surgeon on a merchant vessel trading between London and the West Indies. After two years as assistant apothecary to Mr Murray of Henrietta Street, London, he returned to Scotland in 1732 to establish himself in general medical practice in the parish of Shotts, Lanarkshire. From 1734 to 1736 he studied medicine at the University of Edinburgh, where he became interested in chemistry, and was one of the founders of the Royal Medical Society.
In 1736 he began medical practice in Hamilton, where he rapidly acquired a high reputation. He also continued his study of the natural sciences, especially of chemistry. From 1737 to 1740 William Hunter was his resident pupil, and at one time they proposed to enter into partnership. In 1740 Cullen was awarded the degree of M.D. from Glasgow University. In 1741, he married and started his family. He became ordinary medical attendant to James Douglas, 5th Duke of Hamilton (1703–43), his family, and his livestock. In 1744, following the Duke's death, the Cullens moved to Glasgow.
In Glasgow he gave extramural lectures for the University, on physiology, botany, materia medica, and chemistry. His great abilities, enthusiasm, and use of practical demonstrations for instruction, made him a successful and highly popular teacher, attracting large classes. At the same time he also maintained a medical practice. In 1747, Cullen was awarded Britain's first independent lectureship in Chemistry and was elected President of the Faculty of Physicians and Surgeons of Glasgow. In 1751 he was appointed Professor of the Practice of Medicine, although he continued to lecture on chemistry.
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