Wild type (or wildtype abbreviated wt) refers to the phenotype of the typical form of a species as it occurs in nature. Originally, the wild type was conceptualized as a product of the standard, "normal" allele at a locus, in contrast to that produced by a non-standard, "mutant" allele. It is now appreciated that most or all gene loci exist in a variety of allelic forms, which vary in frequency throughout the geographic range of a species, and that a uniform wild type does not exist. In general, however, the most prevalent allele – e.g., the one with the highest gene frequency - is the one deemed as wild type.
The concept of wild type is useful in some experimental organisms such as fruit flies Drosophila melanogaster, in which the standard phenotypes for features such as eye color or shape and wing form are known to be altered by particular gene mutations that produce distinctive phenotypes, such as "apricot" "bar eyes" or "vestigial wings". Wild-type alleles are indicated with a "+" superscript, for example B+ and vg+ for round eyes and full-size wings, respectively.
Famous quotes containing the words wild and/or type:
“A bestial and violent man will go so far as to kill because he is under the influence of drink, exasperated, or driven by rage and alcohol. He is paltry. He does not know the pleasure of killing, the charity of bestowing death like a caress, of linking it with the play of the noble wild beasts: every cat, every tiger, embraces its prey and licks it even while it destroys it.”
—Colette [Sidonie Gabrielle Colette] (1873–1954)
“One type of rice nourishes one hundred types of people.”
—Chinese proverb.