Wild type (or wildtype abbreviated wt) refers to the phenotype of the typical form of a species as it occurs in nature. Originally, the wild type was conceptualized as a product of the standard, "normal" allele at a locus, in contrast to that produced by a non-standard, "mutant" allele. It is now appreciated that most or all gene loci exist in a variety of allelic forms, which vary in frequency throughout the geographic range of a species, and that a uniform wild type does not exist. In general, however, the most prevalent allele – e.g., the one with the highest gene frequency - is the one deemed as wild type.
The concept of wild type is useful in some experimental organisms such as fruit flies Drosophila melanogaster, in which the standard phenotypes for features such as eye color or shape and wing form are known to be altered by particular gene mutations that produce distinctive phenotypes, such as "apricot" "bar eyes" or "vestigial wings". Wild-type alleles are indicated with a "+" superscript, for example B+ and vg+ for round eyes and full-size wings, respectively.
Famous quotes containing the words wild and/or type:
“The wildest dreams of wild men, even, are not the less true, though they may not recommend themselves to the sense which is most common among Englishmen and Americans to-day. It is not every truth that recommends itself to the common sense. Nature has a place for the wild clematis as well as for the cabbage. Some expressions of truth are reminiscent,—others merely sensible, as the phrase is,—others prophetic.”
—Henry David Thoreau (1817–1862)
“This immediate dependence of language upon nature, this conversion of an outward phenomenon into a type of somewhat in human life, never loses its power to affect us. It is this which gives that piquancy to the conversation of a strong-natured farmer or backwoodsman, which all men relish.”
—Ralph Waldo Emerson (1803–1882)