Luc may refer to:.
In geography:
- Le Luc
- Luc, Hautes-Pyrénées
- Luc, Lozère
- Luc-en-Diois
- Luc-la-Primaube
- Luc-sur-Mer
- Saint-Luc, Switzerland
- Luč, settlement in Croatian Baranja.
In education:
- Limburgs Universitair Centrum, now Hasselt University, Belgium
- Loyola University Chicago
In medicine
- Large unstained cells, referring to big cells that laboratories' equipment can't classify automatically in blood tests.
People:
- Luc Besson (born 1959), a French film director
- Luc Ferrari, a French avant-garde composer
- Luc Jacquet, a film director who wrote and directed March of the Penguins
- Luc Jochimsen (born 1936), a German politician
- Luc Longley (born 1969), an Australian basketball player
- Luc Marquet, a French volleyball player
- Luc Robitaille, a Canadian hockey player
- Luc Sala, a Dutch entrepreneur and writer
- Luc Shellkens, a Dutch football player
- Luc Tuymans, a Belgian contemporary artist
- Luc Vermeulen, a Flemish activist
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- Luc (surname)
In other fields:
- Château de Luc, a French castle-ruin in the town of Luc in the Lozère département
- Luc (Suikoden), a character in the Genso Suikoden series of roleplaying games
- LUC, cryptosystem based on Lucas sequences