Research Findings
Together with Allan Maxam, Gilbert developed a new DNA sequencing method. His approach to the first synthesis of insulin lost out to Genentech's approach which used genes built up from the nucleotides rather than from natural sources.
Gilbert first proposed the existence of introns and exons and explained the evolution of introns in a seminal 1978 "News and Views" paper published in Nature. In 1986, Gilbert proposed the RNA world hypothesis for the origin of life, based on a concept first proposed by Carl Woese in 1967.
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