Surgical Career
In St Vincent's Hospital, he worked with surgeons Dr. Harry Windsor (who had performed Australia's first heart transplant in 1968) and Dr. Mark Shanahan. The advent of anti-rejection drugs in 1980 made heart transplants more feasible, and Chang lobbied politicians and businessmen to raise funds to establish a heart transplant program at St. Vincent's. On 8 April 1984, a team of doctors led by Chang operated on 14-year old Fiona Coote who became Australia's youngest heart transplant patient.
Between 1984 and 1990 Dr. Chang's unit performed over 197 heart transplants and 14 heart-lung transplants. The unit had a high rate of success with 90% of those receiving transplants from the unit surviving beyond the first year. In 1986, Victor Chang was appointed a Companion of the Order of Australia (AC) "In recognition of service to international relations between Australia and China and to medical science".
Concerned about a shortage of organ donors, he arranged financing and assembled a team of scientists and engineers from around the world to develop an artificial heart. That team, working in Singapore, Guangzhou and Sydney, also developed mechanical and tissue heart valves called the St. Vincent's Heart Valves, which were widely implanted throughout Asia. Dr. Chang and his team also made significant progress on the design of an artificial heart. His research projects ended with his death.
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