Development
Vecuronium's structure is derived from the same aminosteroid structure as pancuronium, but it is missing the methyl group on the piperidine nitrogen that is attached to the 'A' ring, making it monoquaternary, like D-tubocurarine. This means it is less potent than pancuronium as a neuromuscular blocking agent. It has the same configuration at all ten stereocentres as pancuronium, and is a single-isomer preparation.
Read more about this topic: Vecuronium Bromide
Famous quotes containing the word development:
“As a final instance of the force of limitations in the development of concentration, I must mention that beautiful creature, Helen Keller, whom I have known for these many years. I am filled with wonder of her knowledge, acquired because shut out from all distraction. If I could have been deaf, dumb, and blind I also might have arrived at something.”
—Mark Twain [Samuel Langhorne Clemens] (1835–1910)
“Other nations have tried to check ... the fulfillment of our manifest destiny to overspread the continent allotted by Providence for the free development of our yearly multiplying millions.”
—John Louis O’Sullivan (1813–1895)
“I’ve always been impressed by the different paths babies take in their physical development on the way to walking. It’s rare to see a behavior that starts out with such wide natural variation, yet becomes so uniform after only a few months.”
—Lawrence Kutner (20th century)