Vasopressin Analogue

Vasopressin analogues are chemicals similar in function but not necessarily similar in structure to vasopressin (ADH), such as desmopressin.

Desmopressin is administered as an oral spray to treat diseases where ADH is either not being produced in sufficient amounts, or vasopressin's receptors are not being stimulated by the vasopressin. An example of desmopressin's use is for childhood bed-wetting, where it is believed that children's circadian rhythms are not synchronized with normal light-dark cycles, and consequentially the ADH surge normal children experience at night is not experienced in these children. Taking a desmopressin dose 30–45 minutes before sleeping results in concentrated urine production, and the urination reflex experienced when the bladder fills above a certain level is not triggered.


Hypothalamic-pituitary hormones and analogues (H01)
Hypothalamic
GNRH
  • Agonists: Gonadorelin
  • Nafarelin
  • Histrelin
    Antagonists: Cetrorelix
  • Ganirelix
Somatostatin
  • Agonists: Lanreotide
  • Octreotide
  • Pasireotide
  • Vapreotide
Anterior pituitary
ACTH
  • Agonists: Corticotropin
  • Cosyntropin
  • Tetracosactide
GH
  • Agonists: IGF-1 (Mecasermin/Mecasermin rinfabate)
  • Sermorelin
  • Somatrem
    Antagonists: Pegvisomant
TSH
  • Agonists: Thyrotropin
Posterior pituitary
Oxytocin
  • Agonists: Carbetocin
  • Demoxytocin
    Antagonists: Atosiban
Vasopressin
  • Agonists: Argipressin
  • Desmopressin
  • Felypressin
  • Lypressin
  • Ornipressin
  • Terlipressin
    Antagonists: Conivaptan
  • Demeclocycline
  • Lixivaptan
  • Mozavaptan
  • Nelivaptan
  • Relcovaptan
  • Satavaptan
  • Tolvaptan

M: END

anat/phys/devp/horm

noco(d)/cong/tumr, sysi/epon

proc, drug (A10/H1/H2/H3/H5)

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