Symptoms
Many people with this disorder never experience symptoms. When symptoms occur, they can include acute attacks (similar to acute intermittent porphyria), skin damage, or both. Acute attacks usually begin in adulthood and cause abdominal pain, vomiting, diarrhea and constipation. During an attack, a person may also experience muscle weakness, seizures, and mental changes such as anxiety and hallucinations. These signs and symptoms are triggered by nongenetic factors such as certain drugs, dieting or fasting, certain hormones and stress.
Some people with variegate porphyria have skin that is overly sensitive to sunlight. Areas of skin exposed to the sun develop severe blistering, scarring, changes in pigmentation, and increased hair growth. Exposed skin becomes fragile and is easily damaged.
Rarely, the signs and symptoms of variegate porphyria can begin in infancy or early childhood. In such cases, the signs and symptoms are usually more severe than those starting later in life. In addition to the health problems described above, children with this disorder may have mental retardation and grow more slowly than other children.
Read more about this topic: Variegate Porphyria
Famous quotes containing the word symptoms:
“A certain kind of rich man afflicted with the symptoms of moral dandyism sooner or later comes to the conclusion that it isn’t enough merely to make money. He feels obliged to hold views, to espouse causes and elect Presidents, to explain to a trembling world how and why the world went wrong. The spectacle is nearly always comic.”
—Lewis H. Lapham (b. 1935)
“For anyone addicted to reading commonplace books ... finding a good new one is much like enduring a familiar recurrence of malaria, with fever, fits of shaking, strange dreams. Unlike a truly paludismic ordeal, however, the symptoms felt while savoring a collection of one man’s pet quotations are voluptuously enjoyable ...”
—M.F.K. Fisher (1908–1992)
“Protest, evasion, merry distrust, and a delight in mockery are symptoms of health: everything unconditional belongs in pathology.”
—Friedrich Nietzsche (1844–1900)