Vanadium Compounds - Safety

Safety

All vanadium compounds should be considered toxic. Tetravalent VOSO₄ has been reported to be over 5 times more toxic than trivalent V₂O₃. The Occupational Safety and Health Administration (OSHA) has set an exposure limit of 0.05 mg/m3 for vanadium pentoxide dust and 0.1 mg/m3 for vanadium pentoxide fumes in workplace air for an 8-hour workday, 40-hour work week. The National Institute for Occupational Safety and Health (NIOSH) has recommended that 35 mg/m3 of vanadium be considered immediately dangerous to life and health. This is the exposure level of a chemical that is likely to cause permanent health problems or death.

Vanadium compounds are poorly absorbed through the gastrointestinal system. Inhalation exposures to vanadium and vanadium compounds result primarily in adverse effects on the respiratory system. Quantitative data are, however, insufficient to derive a subchronic or chronic inhalation reference dose. Other effects have been reported after oral or inhalation exposures on blood parameters, on liver, on neurological development in rats, and other organs.

There is little evidence that vanadium or vanadium compounds are reproductive toxins or teratogens. Vanadium pentoxide was reported to be carcinogenic in male rats and male and female mice by inhalation in an NTP study, although the interpretation of the results has recently been disputed. Vanadium has not been classified as to carcinogenicity by the United States Environmental Protection Agency.

Vanadium traces in diesel fuels present a corrosion hazard; it is the main fuel component influencing high temperature corrosion. During combustion, it oxidizes and reacts with sodium and sulfur, yielding vanadate compounds with melting points down to 530 °C, which attack the passivation layer on steel, rendering it susceptible to corrosion. The solid vanadium compounds also cause abrasion of engine components.