USS Shaw (DD-68) was a Sampson-class destroyer in the United States Navy during World War I. She was later transferred to the United States Coast Guard as CG-22.
Shaw was laid down on 7 February 1916 by the Mare Island Navy Yard, launched on 9 December 1916, sponsored by Mrs. Virginia Kemper Lynch Millard, and commissioned on 9 April 1917, Lieutenant Commander Milton S. Davis in command.