USS Guardfish has been the name of more than one United States Navy ship, and may refer to:
- USS Guardfish (SS-217), a submarine in commission from 1942 to 1946
- USS Guardfish (SSN-612), a submarine in commission from 1966 to 1992
| This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists. |