U.S. Route 72

U.S. Route 72 is an east–west United States highway that runs for 337 miles (542 km) from southeast Tennessee through northern Alabama and northern Mississippi to southwest Tennessee. The highway's eastern terminus is Chattanooga, Tennessee. Its western terminus is Memphis, Tennessee. It is the only US Highway to have both termini in the same state, yet pass through other states in between. Prior to the US Highway system signage being posted in 1925 the entire route was part of the Lee Highway.