U.S. Route 48

U.S. Route 48 (US 48) is an east–west United States highway that will run 148 miles (238 km) from northern Virginia to central West Virginia. It is being constructed as Corridor H of the Appalachian Development Highway System. While most of the highway has been constructed, only the portion in Virginia is presently designated as US 48.

Two previous highways were designated as US 48. The first, in California, was incorporated into the route of US 50; the second, in western Maryland and West Virginia, was redesignated Interstate 68 (I-68).