U.S. Route 400

U.S. Route 400 is a mostly east–west U.S. Highway, commissioned in 1994. Its route number is a "violation" of the usual AASHTO numbering scheme, as there is no US 0 or US 100.

As of 2004, the highway's eastern terminus is west of Joplin, Missouri at an intersection with Interstate 44, which it shares with U.S. Route 166. It originally ended in Garden City, Kansas; in 1996 it was extended to its current western terminus in Granada, Colorado at an intersection with U.S. Route 385.

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