Treatment
The treatment of urea cycle disorders consists of balancing dietary protein intake in order that the body receive the essential amino acids responsible for cell growth and development, but not so much protein that excessive ammonia is formed. This protein restriction is used in conjunction with medications which provide alternative pathways for the removal of ammonia from the blood. These medications are usually given by way of tube feedings, either via gastrostomy tube (a tube surgically implanted in the stomach) or nasogastric tube through the nose into the stomach. The treatment may also include supplementation with special amino acid formulas developed specifically for urea cycle disorders, multiple vitamins and calcium supplements. Frequent blood tests are required to monitor the disorders and optimize treatment, and frequently hospitalizations are necessary to control the disorder.
At the most extreme end of the spectrum, a few liver transplants have been done successfully as a cure to the disorder. This treatment alternative must be carefully evaluated with medical professionals to determine if potential of success as compared to the potential for new medical concerns.
Read more about this topic: Urea Cycle Disorder
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—Fran Lebowitz (20th century)
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—C. John Sommerville (20th century)
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—James Thurber (18941961)