Other
- Unnatural Selection (album), a 1999 album by Flotsam And Jetsam
- Unnatural Selection (video game), a 1993 video game by Maxis
- "Unnatural Selection", a song on Muse's 2009 album The Resistance
- "Unnatural Selection", an entry in the direct-to-video series P.R.O.B.E., a spin-off of the BBC science-fiction series Doctor Who featuring companion character Liz Shaw.
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