Vice-chancellors
Since the independence of Sudan, highly qualified Sudanese were appointed to the position of University of Khartoum vice chancellor. The first one was Dr. Nasor Alhag Ali and the most notable one is Prof. ELnazeer Dafalla.
University of Khartoum plays a great role in building and qualifying most of the Sudanese leaders.
Politics
- Professor ELnazeer Dafalla.-Vice –chancellor of the University of Khartoum-President of the Round Table Conference-Chairman of First Parliament-Executive Secretary of the United Nations
- Hassan al-Turabi: leader of the National Islamic Front and former dean of Faculty of Law
- Ali Osman Taha: vice president of Sudan
- Mansoor Khalid: former minister of Foreign Affairs
- Alhaj Adam: vice president of Sudan
- John Garang: former leader of Sudan People's Liberation Army/Movement
- Francis Deng: United Nations' Under-Secretary General.
- Ibrahim Abood Ahmed: former commander in chief of Sudanese military forces and president of Sudan
- Sirr Al-Khatim Al-Khalifa: former prime minister and minister of education of Sudan
- Mohamed Ahmed Mahjoob: former prime minister and foreign minister of Sudan
- Babiker Awadalla: former prime minister and foreign minister of Sudan
- Rashid Bakr: former vice president and prime minister of Sudan
- Dr. Al-Jazuli Daf'allah: former prime minister and head of the Sudanese Medical Association of Sudan
Sciences and engineering
- Osama O. Awadelkarim: Professor of Engineering Science and Mechanics and Associate Director for the Center for Nanotechnology Education and Utilization (CNEU) at Penn State.
- Elfatih A.B. Eltahir: Professor of Hydrology and Water Resources at MIT.
- Jaafar M.H. Elmirghani: Professor of Communication Networks and Systems, and Director of the Institute of Integrated Information Systems at the University of Leeds.
Art and education
- Abdalla Eltayeb: scholar in the Arabic language
- Tayeb Salih: novelist
- Leila Aboulela: writer and playwright.
- Mandour Elmahdi: Author of A Short History of the Sudan, Principle of the Institute of Education in Sudan throughout the 1970s and later Director of Education in Saudi Arabia.
- Awn Alsharif Qasim: writer, encyclopedist and scholar of Islamic history and of Sudanese dialects.
- Usamah Mohamad: citizen journalist and Amnesty International prisoner of conscience
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