Knot Structure
Human UCH-L1 and the closely related protein UCHL3 have one of the most complicated knot structure yet discovered for a protein, with five knot crossings. It is speculated that a knot structure may increase a protein's resistance to degradation in the proteasome.
Read more about this topic: Ubiquitin Carboxy-terminal Hydrolase L1
Famous quotes containing the words knot and/or structure:
“A fretful temper will divide
The closest knot that may be tied,
By ceaseless sharp corrosion;
A temper passionate and fierce
May suddenly your joys disperse
At one immense explosion.”
—William Cowper (1731–1800)
“Why does philosophy use concepts and why does faith use symbols if both try to express the same ultimate? The answer, of course, is that the relation to the ultimate is not the same in each case. The philosophical relation is in principle a detached description of the basic structure in which the ultimate manifests itself. The relation of faith is in principle an involved expression of concern about the meaning of the ultimate for the faithful.”
—Paul Tillich (1886–1965)