Function
These proteins were originally characterized by their capacity to induce oncogenic transformation in a specific cell culture system, rat kidney fibroblasts. Application of the transforming growth factors to normal rat kidney fibroblasts induces the cultured cells to proliferate and overgrow, no longer subject to the normal inhibition caused by contact between cells.
Read more about this topic: Transforming Growth Factor
Famous quotes containing the word function:
“To make us feel small in the right way is a function of art; men can only make us feel small in the wrong way.”
—E.M. (Edward Morgan)
“The intension of a proposition comprises whatever the proposition entails: and it includes nothing else.... The connotation or intension of a function comprises all that attribution of this predicate to anything entails as also predicable to that thing.”
—Clarence Lewis (18831964)
“No one, however powerful and successful, can function as an adult if his parents are not satisfied with him.”
—Frank Pittman (20th century)