Transferrin Saturation - Usual Values

Usual Values

Normal reference ranges are:

  • Serum iron: 60–170 μg/dl (10–30μmol/L)
  • TIBC: 240–450 μg/dl
  • Transferrin saturation: 15–50% (males), 12–45% (females)

μg/dl = micrograms per deciliter.

Laboratories often use different units and "normal" may vary by population and the lab techniques used. Look at the individual laboratory reference values to interpret a specific test (for instance, your own).

Pathology: hematology, hematologic diseases of RBCs and megakaryocytes / MEP (D50-69,74, 280-287)
Red
blood cells
↑
Poly-
cythemia
  • Polycythemia vera
↓
Anemia
Nutritional
  • Micro-: Iron deficiency anemia
    • Plummer-Vinson syndrome
  • Macro-: Megaloblastic anemia
    • Pernicious anemia
Hemolytic
(mostly Normo-)
Hereditary
  • enzymopathy: G6PD
  • glycolysis
    • PK
    • TI
    • HK
  • hemoglobinopathy: Thalassemia
    • alpha
    • beta
    • delta
  • Sickle-cell disease/trait
  • HPFH
  • membrane: Hereditary spherocytosis
    • Minkowski-Chauffard syndrome
  • Hereditary elliptocytosis
    • Southeast Asian ovalocytosis
  • Hereditary stomatocytosis
Acquired
  • Autoimmune
    • WAHA
    • CAD
    • PCH
  • membrane
    • PNH
  • MAHA
  • TM
    • HUS
  • Drug-induced autoimmune
  • Drug-induced nonautoimmune
  • Hemolytic disease of the newborn
Aplastic
(mostly Normo-)
  • Hereditary: Fanconi anemia
  • Diamond–Blackfan anemia
  • Acquired: PRCA
  • Sideroblastic anemia
  • Myelophthisic
Blood tests
  • MCV
    • Normocytic
    • Microcytic
    • Macrocytic
  • MCHC
    • Normochromic
    • Hypochromic
Other
  • Methemoglobinemia
  • Sulfhemoglobinemia
  • Reticulocytopenia
Coagulation/
coagulopathy
↑
Hyper-
coagulability
  • primary: Antithrombin III deficiency
  • Protein C deficiency/Activated protein C resistance/Protein S deficiency/Factor V Leiden
  • Prothrombin G20210A
  • acquired:Thrombocytosis
    • essential
  • DIC
    • Congenital afibrinogenemia
    • Purpura fulminans
  • autoimmune
    • Antiphospholipid
↓
Hypo-
coagulability
Thrombocytopenia
  • Thrombocytopenic purpura: ITP
    • Evans syndrome
  • TM
    • TTP
  • Heparin-induced thrombocytopenia
  • May-Hegglin anomaly
Platelet function
  • adhesion
    • Bernard–Soulier syndrome
  • aggregation
    • Glanzmann's thrombasthenia
  • platelet storage pool deficiency
    • Hermansky–Pudlak syndrome
    • Gray platelet syndrome
Clotting factor
  • Hemophilia
    • A/VIII
    • B/IX
    • C/XI
  • von Willebrand disease
  • Hypoprothrombinemia/II
  • XIII
  • Dysfibrinogenemia

M: MYL

cell/phys (coag, heme, immu, gran), csfs

rbmg/mogr/tumr/hist, sysi/epon, btst

drug (B1/2/3+5+6), btst, trns
Medical test: Serology, reference range: Clinical biochemistry blood tests (including BMP, CMP) (CPT 82000–84999)
Fluid/electrolytes
  • electrolytes
    • Na+/K+
    • Cl-/HCO3-
  • renal function, BUN-to-creatinine ratio
    • BUN/Creatinine
  • Ca
  • derived values: Plasma osmolality
  • Serum osmolal gap
Acid-base
  • Arterial blood gas
  • Base excess
  • Anion gap
  • CO2 content
Nutrition
  • Iron tests: Transferrin saturation = Serum iron / Total iron-binding capacity; Ferritin
  • Transferrin
  • Transferrin receptor
Endocrine
  • ACTH stimulation test
  • Thyroid function tests
    • TSH
  • Blood sugar: Glucose test
  • C-peptide
  • Fructosamine
  • Glycated hemoglobin
Metabolic
  • Blood lipids
Cardiovascular
  • Cardiac marker: Troponin test
  • CPK-MB test
  • LDH
  • Myoglobin
  • Glycogen phosphorylase isoenzyme BB
Digestive
  • Liver function tests: protein tests
    • Human serum albumin
    • Serum total protein
  • ALP
  • transaminases
    • ALT
    • AST
    • AST/ALT ratio
  • Bilirubin
    • Unconjugated
    • Conjugated
  • Amylase
  • Lipase
    • Pancreatic lipase

M: URI

anat/phys/devp/cell

noco/acba/cong/tumr, sysi/epon, urte

proc/itvp, drug (G4B), blte, urte

M: END

anat/phys/devp/horm

noco (d)/cong/tumr, sysi/epon

proc, drug (A10/H1/H2/H3/H5)

M: HRT

anat/phys/devp

noco/cong/tumr, sysi/epon, injr

proc, drug (C1A/1B/1C/1D), blte

M: DIG

anat (t, g, p)/phys/devp/enzy

noco/cong/tumr, sysi/epon

proc, drug (A2A/2B/3/4/5/6/7/14/16), blte


Read more about this topic:  Transferrin Saturation

Famous quotes containing the words usual and/or values:

    “Summer has set in with its usual severity.”
    —Samuel Taylor Coleridge (1772–1834)

    “The values to which the conservative appeals are inevitably caricatured by the individuals designated to put them into practice.”
    —Harold Rosenberg (1906–1978)