Transferrin

Identifiers Symbols TF; PRO1557; PRO2086; TFQTL1 External IDs OMIM: 190000 MGI: 98821 HomoloGene: 68153 ChEMBL: 4865 GeneCards: TF Gene

Gene Ontology
Molecular function	• protein binding • ferric iron binding • ubiquitin protein ligase binding
Cellular component	• extracellular region • mitochondrion • early endosome • late endosome • coated pit • basal plasma membrane • endosome membrane • cytoplasmic membrane-bounded vesicle • apical plasma membrane • endocytic vesicle • secretory granule • basal part of cell • perinuclear region of cytoplasm • recycling endosome
Biological process	• platelet degranulation • cellular iron ion homeostasis • blood coagulation • platelet activation • transferrin transport • transmembrane transport
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7018 22041 Ensembl ENSG00000091513 ENSMUSG00000032554 UniProt P02787 Q921I1 RefSeq (mRNA) NM_001063.3 NM_133977.2 RefSeq (protein) NP_001054.1 NP_598738.1 Location (UCSC) Chr 3:
133.46 – 133.5 Mb Chr 9:
103.2 – 103.23 Mb PubMed search

Transferrin

Identifiers

Symbol

Transferrin

Pfam

PF00405

InterPro

IPR001156

PROSITE

PDOC00182

SCOP

1lcf

SUPERFAMILY

1lcf

OPM superfamily

161

OPM protein

1lfc

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe
PDBsum	structure summary

Transferrins are iron-binding blood plasma glycoproteins that control the level of free iron in biological fluids. Human transferrin is encoded by the TF gene.