Sultan Iskandar may refer to several rulers named Iskandar with the title of sultan:
- Sultan Ali Iskandar Shah, 19th Sultan of Johor
- Sultan Mahmud Iskandar Shah, 11th Sultan of Perak
- Sultan Iskandar Dzulkarnain, 15th Sultan of Perak
- Sultan Iskandar Ibrahim, ruler of Maldives, 17th century
- Sultan Iskandar of Johor (1932-2010), 8th Yang di-Pertuan Agong of Malaysia the 24th Sultan of Johor
- Sultan Iskandar Muda (1583-1636), Acehnese ruler (r. 1607-36)