Skin Disease
An inability to correctly maintain the skin barrier function due to the dysregulation of epidermal components can lead to skin disorders. For example, a failure to modulate the activity of kallikreins via the disruption of the protease inhibitor LEKTI causes the debilitating disorder Netherton syndrome.
Read more about this topic: Stratum Corneum
Famous quotes containing the words skin and/or disease:
“The bottom line on bonding with multiples seems to be that if you see bonding as a static event—a moment in time at which you must have eye contact and skin contact simultaneously with two or more infants—you may indeed be in trouble.”
—Pamela Patrick Novotny (20th century)
“Health is a state of complete physical, mental and social well-being, and not merely the absence of disease or infirmity.”
—Constitution of the World Health Organization.