Skin Disease
An inability to correctly maintain the skin barrier function due to the dysregulation of epidermal components can lead to skin disorders. For example, a failure to modulate the activity of kallikreins via the disruption of the protease inhibitor LEKTI causes the debilitating disorder Netherton syndrome.
Read more about this topic: Stratum Corneum
Famous quotes containing the words skin and/or disease:
“Just as bones, tissues, intestines, and blood vessels are enclosed in a skin that makes it possible to bear the sight of a human being, so the agitations and passions of the soul are wrapped up in vanity: it is the soul’s skin.”
—Friedrich Nietzsche (1844–1900)
“There is a disease to which plays as well as men become liable with advancing years. In men it is called doting, in plays dating. The more topical the play the more it dates.”
—George Bernard Shaw (1856–1950)