Skin Disease
An inability to correctly maintain the skin barrier function due to the dysregulation of epidermal components can lead to skin disorders. For example, a failure to modulate the activity of kallikreins via the disruption of the protease inhibitor LEKTI causes the debilitating disorder Netherton syndrome.
Read more about this topic: Stratum Corneum
Famous quotes containing the words skin and/or disease:
“Anyone who tries to keep track of what is happening in China is going to end up by wearing all the skin of his left ear from twirling around on it.”
—Robert Benchley (1889–1945)
“In a country where misery and want were the foundation of the social structure, famine was periodic, death from starvation common, disease pervasive, thievery normal, and graft and corruption taken for granted, the elimination of these conditions in Communist China is so striking that negative aspects of the new rule fade in relative importance.”
—Barbara Tuchman (1912–1989)