Skin Disease
An inability to correctly maintain the skin barrier function due to the dysregulation of epidermal components can lead to skin disorders. For example, a failure to modulate the activity of kallikreins via the disruption of the protease inhibitor LEKTI causes the debilitating disorder Netherton syndrome.
Read more about this topic: Stratum Corneum
Famous quotes containing the words skin and/or disease:
“You flicker. I cannot touch you.
I put my hands among the flames. Nothing burns.
And it exhausts me to watch you
Flickering like that, wrinkly and clear red, like the skin of a mouth.”
—Sylvia Plath (1932–1963)
“The peace loving nations must make a concerted effort in opposition to those violations of treaties and those ignorings of humane instincts which today are creating a state of international anarchy and instability from which there is no escape through mere isolation or neutrality.... When an epidemic of physical disease starts to spread, the community approves and joins in a quarantine of the patients in order to protect the health of the community against the spread of the disease.”
—Franklin D. Roosevelt (1882–1945)