Skin Disease
An inability to correctly maintain the skin barrier function due to the dysregulation of epidermal components can lead to skin disorders. For example, a failure to modulate the activity of kallikreins via the disruption of the protease inhibitor LEKTI causes the debilitating disorder Netherton syndrome.
Read more about this topic: Stratum Corneum
Famous quotes containing the words skin and/or disease:
“The snake that cannot shed its skin perishes. Likewise those spirits who are prevented from changing their opinions; they cease to be spirits.”
—Friedrich Nietzsche (1844–1900)
“Hastiness and superficiality are the psychic diseases of the twentieth century, and more than anywhere else this disease is reflected in the press.”
—Alexander Solzhenitsyn (b. 1918)